General Cell Based Assays
STEMCELL Technologies Busulfan, Size: 100 g
Inhibit proliferation of cancer cells by creating DNA breaks and DNA crosslinks with busulfan (Iwamoto et al.). Highly potent and cell-permeable busulfan forms interstrand crosslinks between the DNA bases guanine and adenine and between guanine and guanine (Ponti et al.). DNA breakage induced by busulfan-mediated DNA crosslinking induces senescence in cells (Chen et al.).
Abcam Factor Xa Assay Kit.
Factor Xa Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress CXCR7 Activated GPCR Internalization Assay, 10pl Kit. (93-0738E3CP27L)
The PathHunter CXCR7 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CXCR7 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CXCR7. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CXCR7-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human IL-17RB ASY
The R-PLEX Human IL-17RB Assay Kit from Meso Scale Discovery is a multiplex immunoassay that enables the simultaneous measurement of IL-17RB in human serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity up to a 7-log dynamic range and requires low sample volume The kit includes a 96-well plate pre-coated with capture antibodies detection antibodies calibrators and controls for the quantitative analysis of IL-17RB This assay allows for efficient and reproducible quantification of IL-17RB levels
Meso Scale Discovery R-PLEX AB38 4G8 ASY
The Meso Scale Discovery R-PLEX Human Abeta38 (4G8) Assay Kit is a multiplex immunoassay that measures Abeta38 in human serum plasma CSF and cell culture supernatants It uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements This assay kit includes a plate coated with a 4G8 antibody to capture Abeta38 It also includes detection antibodies standards buffers calibrators controls and substrate The kit is for research use only and not for use in diagnostic procedures It allows sensitive accurate and reproducible quantification of Abeta38 levels
Eurofins Discoverx PathHunter eXpress GPR30 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0373E2ACP2M)
The PathHunter GPR30 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR30 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR30 and EA-tagged β-Arrestin-2. Activation of GPR30 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cell Biolabs Inc OxiSelect™ Hydrogen Peroxide/Peroxidase Assay Kit (Colorimetric), 500 assays
Hydrogen peroxide is one of the most stable and ubiquitous of the reactive oxygen species (ROS), making it ideal for testing the presence of ROS. Cell Biolabs' OxiSelect™ Hydrogen Peroxide/Peroxidase Assay Kit is a sensitive colorimetric assay for the quantitation of hydrogen peroxide or peroxidase. The H2O2 or peroxidase content in unknowns is compared with a standard curve in a standard 96-well colorimetric plate reader. The kit can measure hydrogen peroxide levels as low as 0.8 µM, or peroxidase levels as low as 0.16 mU/mL. Each kit provides sufficient reagents for 500 assays including standards and unknown samples.
Eurofins Discoverx PathHunter eXpress mFPR2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-1034E2MCP2M)
The PathHunter mFPR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. formylpeptides) based activation of mFPR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mFPR2 and EA-tagged β-Arrestin-2. Activation of mFPR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Cell Plating 26 Reagent, 100. (93-0563R26A)
AssayComplete Cell Plating 26 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress TORC2 Nuclear Translocation Assay, 10pl Kit. (93-0813E3CP19L)
The PathHunter eXpress TORC2 Nuclear Translocation Assay provides an easy-to-use cell based assay to study drug candidates affecting the CRTC/CREB pathway. This kit assesses ligand (e.g. forskolin) based pathway activation via detection of resulting TORC2 (CRTC2) nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged TORC2 (CRTC2) and nuclear localized EA. Upon pathway activation, induced nuclear translocation of TORC2 leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR35 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0942E2CP2L)
The PathHunter GPR35 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. zaprinast) based activation of GPR35 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR35 and EA-tagged β-Arrestin-2. Activation of GPR35 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Total SMAD2 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total SMAD2 Detection Kit, 500 Assay Points
American Research Products Inc Rat a Smooth muscle actin a S
Rat a-Smooth muscle actin a-SMA ELISA Kit from CUSABIO Detection Range 0 78 ng/mL-50 ng/mL Sensitivity 0 195 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Revvity Health Sciences Inc HTRF α-Tubulin Housekeeping Kit, 10,000 Assay Points
HTRF α-Tubulin Housekeeping Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-BAD (Ser112) Detection Kit, 500 Assay Points
HTRF Human Phospho-BAD (Ser112) Detection Kit, 500 Assay Points